Cloned (Comment) | Organism |
---|---|
expression in Sf9 cells of full-length protein and of Gal4-dHDAC1, consisting of the N-terminal 147 amino acid residues of the yeast Gal4 protein fused to the N terminus of full-length dHDAC1 protein | Drosophila melanogaster |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
FR901228 | Gal4-dHDAC1, consisting of the N-terminal 147 amino acid residues of the yeast Gal4 protein fused to the N terminus of full-length dHDAC1 protein, but not dHDAC1, is able to repress transcription in vitro. Transcriptional repression is blocked by the enzyme inhibitor FR901228 | Drosophila melanogaster |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila melanogaster | - |
isoform dHDAC1, i.e. dRPD3 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Gal4-dHDAC1, consisting of the N-terminal 147 amino acid residues of the yeast Gal4 protein fused to the N terminus of full-length dHDAC1 protein, but not dHDAC1, is able to repress transcription in vitro. Transcriptional repression is blocked by the enzyme inhibitor FR901228 | Drosophila melanogaster | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
dRPD3 | - |
Drosophila melanogaster |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
additional information | deacetylation by isoform dHDAC1 does not require any additional cofactors | Drosophila melanogaster |