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Literature summary for 3.5.1.92 extracted from

  • Ricci, G.; Nardini, M.; Chiaraluce, R.; Dupre, S.; Cavallini, D.
    Interaction of pantetheinase with sulfhydryl reagents and disulfides (1986), Biochim. Biophys. Acta, 870, 82-91.
    View publication on PubMed
Search for more literature for 3.5.1.92

Inhibitors

Inhibitors Comment Organism Structure
2-Nitro-5-thiocyanobenzoate 0.1 mM, 15 min, 10% residual activity in absence of substrate S-pantetheine-3-pyruvate, 51% residual activity in presence of the substrate S-pantetheine-3-pyruvate Sus scrofa
4,4'-dithiodipyridine 0.01 mM, 15 min, no residual activity in absence of substrate S-pantetheine-3-pyruvate, 13% residual activity in presence of the substrate S-pantetheine-3-pyruvate Sus scrofa
5,5'-dithiobis(2-nitrobenzoate) 0.1 mM, 15 min, 78% residual activity in absence of substrate S-pantetheine-3-pyruvate, 33% residual activity in presence of the substrate S-pantetheine-3-pyruvate Sus scrofa
Bromopyruvate 0.1 mM, 15 min, 2% residual activity in absence of substrate S-pantetheine-3-pyruvate, 76% residual activity in presence of the substrate S-pantetheine-3-pyruvate Sus scrofa
cystamine 0.1 mM, 15 min, 41% residual activity in absence of substrate S-pantetheine-3-pyruvate, 60% residual activity in presence of the substrate S-pantetheine-3-pyruvate Sus scrofa
cystine 5 mM, 15 min, 100% residual activity in absence of substrate S-pantetheine-3-pyruvate, 32% residual activity in presence of the substrate S-pantetheine-3-pyruvate Sus scrofa
H2O2 0.1 mM, 15 min, 17% residual activity in absence of substrate S-pantetheine-3-pyruvate, 47% residual activity in presence of the substrate S-pantetheine-3-pyruvate Sus scrofa
iodoacetamide 0.1 mM, 15 min, 0.5% residual activity in absence of substrate S-pantetheine-3-pyruvate, 72% residual activity in presence of the substrate S-pantetheine-3-pyruvate Sus scrofa
iodoacetate 1 mM, 15 min, 16% residual activity in absence of substrate S-pantetheine-3-pyruvate, 90% residual activity in presence of the substrate S-pantetheine-3-pyruvate Sus scrofa
additional information no inhibition by 5 mM GSSG in absence or presence of substrate S-pantetheine-3-pyruvate Sus scrofa
NaAsO2 1 mM, 15 min, 90% residual activity in absence or presence of substrate S-pantetheine-3-pyruvate Sus scrofa
NEM 1 mM, 15 min, no residual activity in absence of substrate S-pantetheine-3-pyruvate, 54% residual activity in presence of the substrate S-pantetheine-3-pyruvate Sus scrofa
o-Iodosobenzoate 0.05 mM, 15 min, 15% residual activity in absence of substrate S-pantetheine-3-pyruvate, 53% residual activity in presence of the substrate S-pantetheine-3-pyruvate Sus scrofa
p-aminophenylarsine oxide 1 mM, 15 min, 45% residual activity in absence of substrate S-pantetheine-3-pyruvate, 55% residual activity in presence of the substrate S-pantetheine-3-pyruvate Sus scrofa
pantethine 0.01 mM, 15 min, no residual activity in absence of substrate S-pantetheine-3-pyruvate, 52% residual activity in presence of the substrate S-pantetheine-3-pyruvate Sus scrofa
PCMB 0.0001 mM, 15 min, 1% residual activity in absence of substrate S-pantetheine-3-pyruvate, 68% residual activity in presence of the substrate S-pantetheine-3-pyruvate Sus scrofa
Phenylarsine oxide 1 mM, 15 min, 48% residual activity in absence of substrate S-pantetheine-3-pyruvate, 52% residual activity in presence of the substrate S-pantetheine-3-pyruvate Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
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-
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Source Tissue

Source Tissue Comment Organism Textmining
kidney
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 Sus scrofa
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-pantetheine-3-pyruvate + H2O
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 Sus scrofa S-cysteamine 3-pyruvate + pantothenate
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 ?