General Stability | Organism |
---|---|
formamidase I more heat-stable than formamidase II | Drosophila melanogaster |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.83 | - |
N-formyl-L-kynurenine | formamidase II | Drosophila melanogaster | |
5 | - |
N-formyl-L-kynurenine | formamidase I | Drosophila melanogaster |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
30500 | - |
formamidase II, gel filtration | Lithobates pipiens |
31000 | - |
formamidase II, gel filtration | Drosophila melanogaster |
36000 | - |
formamidase II, gel filtration | Mus musculus |
36500 | - |
formamidase II, gel filtration | Drosophila virilis |
58500 | - |
formamidase I, gel filtration | Saccharomyces cerevisiae |
59000 | - |
formamidase I, gel filtration | Gallus gallus |
59000 | - |
formamidase I, gel filtration | Bos taurus |
60000 | - |
- |
Gallus gallus |
60000 | - |
formamidase I, gel filtration | Drosophila melanogaster |
60000 | - |
formamidase I, gel filtration | Musca domestica |
60000 | - |
formamidase I, gel filtration | Drosophila virilis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-formyl-L-kynurenine + H2O | Gallus gallus | - |
L-kynurenine + formate | - |
? | |
N-formyl-L-kynurenine + H2O | Drosophila melanogaster | - |
L-kynurenine + formate | - |
? | |
N-formyl-L-kynurenine + H2O | Saccharomyces cerevisiae | - |
L-kynurenine + formate | - |
? | |
N-formyl-L-kynurenine + H2O | Bos taurus | - |
L-kynurenine + formate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
formamidase I | - |
Drosophila melanogaster | - |
2 forms, formamidase I and II | - |
Drosophila virilis | - |
2 forms, formamidase I and II | - |
Gallus gallus | - |
chicken, formamidase I | - |
Lithobates pipiens | - |
frog, formamidase II | - |
Mus musculus | - |
formamidase II | - |
Musca domestica | - |
housefly, formamidase I | - |
Saccharomyces cerevisiae | - |
1 form, formamidase I | - |
Purification (Comment) | Organism |
---|---|
to homogeneity, chromatography techniques, 2 forms | Drosophila melanogaster |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cell culture | - |
Saccharomyces cerevisiae | - |
liver | - |
Gallus gallus | - |
liver | - |
Mus musculus | - |
liver | - |
Bos taurus | - |
liver | - |
Lithobates pipiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.26 | - |
formamidase I | Drosophila melanogaster |
0.48 | - |
formamidase II | Drosophila melanogaster |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-formyl-L-kynurenine + H2O | - |
Gallus gallus | L-kynurenine + formate | - |
? | |
N-formyl-L-kynurenine + H2O | - |
Drosophila melanogaster | L-kynurenine + formate | - |
? | |
N-formyl-L-kynurenine + H2O | - |
Saccharomyces cerevisiae | L-kynurenine + formate | - |
? | |
N-formyl-L-kynurenine + H2O | - |
Bos taurus | L-kynurenine + formate | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.5 | 8 | formamidase II | Drosophila melanogaster |
6.7 | 7.8 | formamidase I | Drosophila melanogaster |