Inhibitors | Comment | Organism | Structure |
---|---|---|---|
gamma-Glu-Ala-Gly-CHO | most probably captures Cys59 and accumulates as the tetrahedral adduct in the amidase active site. Binding of phosphinophosphate in the Gsp synthetase active site potentiates the inhibition affinity for the aldehyde at the Gsp amidase active site by two orders of magnitude | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
bifunctional enzyme glutathionylspermidine synthetase/amidase | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathionylspermidine + H2O | - |
Escherichia coli | glutathione + spermidine | - |
? |