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Literature summary for 3.5.1.61 extracted from

  • Tangendjaja, B.; Lowry, J.B.; Wills, R.B.H.
    Optimisation of conditions for the degradation of mimosine in Leucaena leucocephala leaf (1984), J. Sci. Food Agric., 35, 613-616.
No PubMed abstract available
Search for more literature for 3.5.1.61

Application

Application Comment Organism
nutrition implication for reducing the toxicity of Leucaena used for stock feed, the product 3-hydroxy-4(1H)-pyrid-4-one, DHP, is goitrogenic in animals but is less toxic than mimosine, conversion of mimosine to DHP is therefore beneficial for the use of Leucaena as animal feed Leucaena leucocephala

Organism

Organism UniProt Comment Textmining
Leucaena leucocephala
-
 (Lam) de Wit cv. Cunningham
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
 Leucaena leucocephala
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-2-amino-3-(3-hydroxy-4-oxo-4H-pyridin-1-yl)propanoate + H2O free toxic amino acid mimosine, 3-(3-hydroxy-4-oxo-1(4H)-pyridyl)-L-alanine, beta-[N-(3-hydroxy-4(1H)-pyridone)]-alpha-aminopropionic acid, beta-[N-(3-hydroxy-4-oxypyridyl)]-alpha-aminopropionic acid Leucaena leucocephala 3-hydroxy-4(1H)-pyrid-4-one + L-serine DHP, less toxic than mimosine ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
45
-
-
 Leucaena leucocephala

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
35 65 appreciable activity between Leucaena leucocephala

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
70
-
 partial denaturation of the enzyme at Leucaena leucocephala

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
-
 Leucaena leucocephala

pH Range

pH Minimum pH Maximum Comment Organism
additional information
-
-
 Leucaena leucocephala