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Literature summary for 3.5.1.56 extracted from

  • Dziewit, L.; Dmowski, M.; Baj, J.; Bartosik, D.
    Plasmid pAMI2 of Paracoccus aminophilus JCM 7686 carries N,N-dimethylformamide degradation-related genes whose expression is activated by a LuxR family regulator (2010), Appl. Environ. Microbiol., 76, 1861-1869.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
N,N-dimethylformamide + H2O Paracoccus aminophilus an enzyme of high substrate specificity that catalyzes the first step in the degradation of N,N-dimethylformamide dimethylamine + formate
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Organism

Organism UniProt Comment Textmining
Paracoccus aminophilus
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JCM 7686
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Reaction

Reaction Comment Organism Reaction ID
N,N-dimethylformamide + H2O = dimethylamine + formate an enzyme of high substrate specificity that catalyzes the first step in the degradation of N,N-dimethylformamide Paracoccus aminophilus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N,N-dimethylformamide + H2O an enzyme of high substrate specificity that catalyzes the first step in the degradation of N,N-dimethylformamide Paracoccus aminophilus dimethylamine + formate
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?
N,N-dimethylformamide + H2O N,N-dimethylformamide, a toxic solvent used in the chemical industry, is frequently present in industrial waste Paracoccus aminophilus dimethylamine + formate
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Subunits

Subunits Comment Organism
More plasmid pAMI2 of Paracoccus aminophilus JCM 7686 carries genetic information which is crucial for the methylotrophic growth, using N,N-dimethylformamide as the sole source of carbon and energy. The plasmid carries a three-gene cluster coding for DmfR, a transcription regulator of the LuxR familiy and two subunits, DmfA1 and DmfA2 of N,N-dimethylformamidase, an enzyme of high substrate specificity that catalyzes the first step in the degradation of N,N-dimethylformamide Paracoccus aminophilus

Synonyms

Synonyms Comment Organism
DFMase
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Paracoccus aminophilus
N,N-dimethylformamidase
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Paracoccus aminophilus

General Information

General Information Comment Organism
physiological function plasmid pAMI2 of Paracoccus aminophilus JCM 7686 carries genetic information which is crucial for the methylotrophic growth, using N,N-dimethylformamide as the sole source of carbon and energy. The plasmid carries a three-gene cluster coding for DmfR, a transcription regulator of the LuxR familiy and two subunits, DmfA1 and DmfA2 of N,N-dimethylformamidase, an enzyme of high substrate specificity that catalyzes the first step in the degradation of N,N-dimethylformamide Paracoccus aminophilus