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Literature summary for 3.5.1.5 extracted from

  • Sheng, G.H.; Chen, X.F.; Li, J.; Chen, J.; Xu, Y.; Han, Y.W.; Yang, T.; You, Z.; Zhu, H.L.
    Synthesis, crystal structures and urease inhibition of N-(2-bromobenzylidene)-2-(4-nitrophenoxy) acetohydrazide and N-(4-nitrobenzylidene)-2-(4-nitrophenoxy)acetohydrazide (2015), Acta Chim. Slov., 62, 940-946 .
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
N'-(2-bromobenzylidene)-2-(4-nitrophenoxy)acetohydrazide
-
 Helicobacter pylori
N'-(4-nitrobenzylidene)-2-(4-nitrophenoxy)acetohydrazide
-
 Helicobacter pylori

Organism

Organism UniProt Comment Textmining
Helicobacter pylori
-
-
-
Helicobacter pylori ATCC 43504
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
urea + H2O
-
 Helicobacter pylori CO2 + 2 NH3
-
 ?
urea + H2O
-
 Helicobacter pylori ATCC 43504 CO2 + 2 NH3
-
 ?

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0084
-
 23°C, pH not specified in the publication Helicobacter pylori N'-(2-bromobenzylidene)-2-(4-nitrophenoxy)acetohydrazide
0.0202
-
 23°C, pH not specified in the publication Helicobacter pylori N'-(4-nitrobenzylidene)-2-(4-nitrophenoxy)acetohydrazide