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Literature summary for 3.5.1.5 extracted from

  • Kumar, S.; Kayastha, A.M.
    Inhibition studies of soybean (Glycine max) urease with heavy metals, sodium salts of mineral acids, boric acid, and boronic acids (2010), J. Enzyme Inhib. Med. Chem., 25, 646-652.
    View publication on PubMed
Search for more literature for 3.5.1.5

Inhibitors

Inhibitors Comment Organism Structure
4-bromophenylboronic acid competitive inhibition Glycine max
Ag+ time-dependent inhibition studies exhibit biphasic kinetics with heavy metal ions Glycine max
Boric acid competitive inhibition Glycine max
butylboronic acid competitive inhibition Glycine max
Cu2+ time-dependent inhibition studies exhibit biphasic kinetics with heavy metal ions Glycine max
Hg2+ time-dependent inhibition studies exhibit biphasic kinetics with heavy metal ions Glycine max
NaF
-
 Glycine max
phenylboronic acid competitive inhibition Glycine max

Organism

Organism UniProt Comment Textmining
Glycine max
-
-
-

Synonyms

Synonyms Comment Organism
urease
-
 Glycine max

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Glycine max

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
 assay at Glycine max

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.2
-
 Boric acid pH 7.0, 37°C Glycine max
0.22
-
 4-bromophenylboronic acid pH 7.0, 37°C Glycine max
1.3
-
 NaF pH 7.0, 37°C Glycine max
1.5
-
 butylboronic acid pH 7.0, 37°C Glycine max
2
-
 phenylboronic acid pH 7.0, 37°C Glycine max

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.000000023
-
 pH 7.0, 37°C Glycine max Ag+
0.000071
-
 pH 7.0, 37°C Glycine max Hg2+
0.0033
-
 pH 7.0, 37°C Glycine max Cu2+