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Literature summary for 3.5.1.5 extracted from
- Inactivation of jack bean urease by N-ethylmaleimide: pH dependence, reversibility and thiols influence (2008), J. Enzyme Inhib. Med. Chem., 23, 514-520.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| N-ethylmaleimide | irreversible inactivation | Canavalia ensiformis |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Canavalia ensiformis | - |
Jack bean | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| urea + H2O | - |
Canavalia ensiformis | CO2 + 2 NH3 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| homohexamer | 2 Ni2+/subunit | Canavalia ensiformis |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Urea amidohydrolase | - |
Canavalia ensiformis |
| urease | - |
Canavalia ensiformis |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 7 | - |
N-ethylmaleimide | Ki(fast), pH 6.4 | Canavalia ensiformis | |
| 7.5 | - |
N-ethylmaleimide | Ki(slow), pH 6.4 | Canavalia ensiformis | |
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