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Literature summary for 3.5.1.48 extracted from
- Deacetylation of N8-acetylspermidine by subcellular fractions of rat tissue (1978), Arch. Biochem. Biophys., 189, 20-27.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| dithiothreitol | 93% increase of activity at 10 mM | Rattus sp. |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Rattus sp. | 5829 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus sp. | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | 4% activity of that in liver | Rattus sp. | - |
| heart | 10% activity of that in liver | Rattus sp. | - |
| kidney | 28% activity of that in liver | Rattus sp. | - |
| liver | highest activity level | Rattus sp. | - |
| lung | 21% activity of that in liver | Rattus sp. | - |
| serum | 0.2% activity of that in liver | Rattus sp. | - |
| skeletal muscle | 2.5% activity of that in liver | Rattus sp. | - |
| spleen | 47% activity of that in liver | Rattus sp. | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| N8-acetylspermidine + H2O | - |
Rattus sp. | acetate + spermidine | - |
? | |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 65 | - |
complete inactivation after 10 min | Rattus sp. |
pH Stability
| pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|
| 7.3 | 9 | activity not significantly affected within | Rattus sp. |
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