Literature summary for 3.5.1.41 extracted from

Zhao, P.; Zhang, X.; Liu, X.; Zhao, X.; Yu, R.; Dong, W.; Ma, E.; Zhang, J.; Zhang, M.
Eukaryotic expression, affinity purification and enzyme activity of chitin deacetylase in Locusta migratoria (2017), Sci. Agric. Sin., 50, 1057-1066 .

No PubMed abstract available

Search for more literature for 3.5.1.41

Application

Application	Comment	Organism
drug development	the isozyme might be a good drug target	Locusta migratoria

Cloned(Commentary)

Cloned (Comment)	Organism
gene cda1, recombinant expression of His-tagged enzyme in Spodoptera frugiperda Sf9 cells via transfection with the baculovirus method	Locusta migratoria
gene cda2a, recombinant expression of His-tagged enzyme in Spodoptera frugiperda Sf9 cells via transfection with the baculovirus method	Locusta migratoria
gene cda2b, recombinant expression of His-tagged enzyme in Spodoptera frugiperda Sf9 cells via transfection with the baculovirus method	Locusta migratoria

Organism

Organism	UniProt	Comment	Textmining
Locusta migratoria	A0A2R2PTF2	-	-
Locusta migratoria	A0A2R2PTF4	-	-
Locusta migratoria	A0A2R2PTG7	-	-

Purification (Commentary)

Purification (Comment)	Organism
recombinant His-tagged enzyme from Spodoptera frugiperda Sf9 cells by nickel affinity and anion exchange chromatography	Locusta migratoria

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
additional information	-	purified reombinant isozyme CDA1, 0.268 U/microliter	Locusta migratoria
additional information	-	purified reombinant isozyme CDA2a, 0.354 U/microliter	Locusta migratoria
additional information	-	purified reombinant isozyme CDA2b, 0.228 U/microliter	Locusta migratoria

Subunits

Subunits	Comment	Organism
More	the enzyme contains four structural domains: a signal peptide, a chitin-binding peritrophin-A domain, a low-density lipoprotein receptor class A (LDLa) domain, and a catalytic domain	Locusta migratoria

Synonyms

Synonyms	Comment	Organism
CDA1	-	Locusta migratoria
cda2aa	-	Locusta migratoria
cda2b	-	Locusta migratoria
chitin deacetylase 1	-	Locusta migratoria
chitin deacetylase 2	-	Locusta migratoria
LmCDA1	-	Locusta migratoria
LmCDA2a	-	Locusta migratoria
LmCDA2b	-	Locusta migratoria

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Release 2023.1 (January 2023)