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Literature summary for 3.5.1.33 extracted from
- Glucosamine metabolism. N-acetylglucosamine deacetylase (1957), J. Biol. Chem., 226, 115-124.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| EDTA | - |
Escherichia coli |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 120 | - |
N-acetyl-D-glucosamine | - |
Escherichia coli | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| N-acetyl-D-glucosamine + H2O | Escherichia coli | - |
D-glucosamine + acetate | - |
? | |
| N-acetyl-D-glucosamine + H2O | Escherichia coli B / ATCC 11303 | - |
D-glucosamine + acetate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Clostridium cadaveris | - |
- |
- |
| Enterococcus faecalis | - |
- |
- |
| Escherichia coli | - |
B | - |
| Escherichia coli | - |
ATCC 4157 | - |
| Escherichia coli | - |
stain K-12 | - |
| Escherichia coli B / ATCC 11303 | - |
B | - |
| Saccharomyces cerevisiae | - |
- |
- |
Storage Stability
| Storage Stability | Organism |
|---|---|
| 1°C, 4 h, complete loss of activity | Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| N-acetyl-D-galactosamine + H2O | - |
Escherichia coli | galactosamine + acetate | - |
? | |
| N-acetyl-D-galactosamine + H2O | - |
Escherichia coli B / ATCC 11303 | galactosamine + acetate | - |
? | |
| N-acetyl-D-glucosamine + H2O | - |
Escherichia coli | D-glucosamine + acetate | - |
? | |
| N-acetyl-D-glucosamine + H2O | - |
Saccharomyces cerevisiae | D-glucosamine + acetate | - |
? | |
| N-acetyl-D-glucosamine + H2O | - |
Enterococcus faecalis | D-glucosamine + acetate | - |
? | |
| N-acetyl-D-glucosamine + H2O | - |
Clostridium cadaveris | D-glucosamine + acetate | - |
? | |
| N-acetyl-D-glucosamine + H2O | - |
Escherichia coli B / ATCC 11303 | D-glucosamine + acetate | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | 8.5 | - |
Escherichia coli |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 6 | 9.5 | pH 6: 5% of maximal activity, pH 9.5: 10% of maximal activity | Escherichia coli |
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Release 2023.1 (January 2023)
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