Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-(acetamidomethylene)succinate + 2 H2O | Mesorhizobium loti | - |
acetate + succinate semialdehyde + NH3 + CO2 | - |
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Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mesorhizobium loti | Q988D4 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-(acetamidomethylene)succinate + 2 H2O | - |
Mesorhizobium loti | acetate + succinate semialdehyde + NH3 + CO2 | - |
? | |
2-(acetamidomethylene)succinate + 2 H2O | molecular docking of two substrate isomers E- and Z-2-(acetamidomethylene)succinate to the hydrolase, molecular dynamics simulations and calculations of binding free energies, overview | Mesorhizobium loti | acetate + succinate semialdehyde + NH3 + CO2 | - |
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Synonyms | Comment | Organism |
---|---|---|
E-2AMS hydrolase | - |
Mesorhizobium loti |
General Information | Comment | Organism |
---|---|---|
metabolism | binding of (E)-2-(acetamidomethylene)succinate to the enzyme is crucial for biological function of the enzyme and the last step reaction of vitamin B6 biological degradation | Mesorhizobium loti |
additional information | molecular docking of the two substrate isomers E- and Z-2-(acetamidomethylene)succinate to the hydrolase, molecular dynamics simulations and calculations of binding free energies, usage of X-ray crystal structure of E-2AMS hydrolase, PDB ID 3KXP, overview | Mesorhizobium loti |
physiological function | binding of (E)-2-(acetamidomethylene)succinate to the enzyme is crucial for biological function of the enzyme and the last step reaction of vitamin B6 biological degradation | Mesorhizobium loti |