Any feedback?
Literature summary for 3.5.1.28 extracted from
- AmiC functions as an N-acetylmuramyl-l-alanine amidase necessary for cell separation and can promote autolysis in Neisseria gonorrhoeae (2006), J. Bacteriol., 188, 7211-7221.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | knockout mutants of amiC show no release of disaccharide units and diminished cell separation, but still undergo autolysis in stationary phase of the organism indicating that not only AmiC is responsible for autolysis, in growth phase the cell lysis rate is increased in the mutant, deletion of amiC increases outer membrane permeability | Neisseria gonorrhoeae |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Neisseria gonorrhoeae | 16020 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Neisseria gonorrhoeae | the enzyme performs cell wall lysis as peptidoglycan-degrading amidase, but can also promote autolysis in Neisseria gonorrhoeae, other enzymes are also involved in autolysis | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Neisseria gonorrhoeae | - |
gene amiC, several strains, overview | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the enzyme performs cell wall lysis as peptidoglycan-degrading amidase, but can also promote autolysis in Neisseria gonorrhoeae, other enzymes are also involved in autolysis | Neisseria gonorrhoeae | ? | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 22 | - |
autolysis assay at room temperature | Neisseria gonorrhoeae |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
autolysis assay at | Neisseria gonorrhoeae |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
