Inhibitors | Comment | Organism | Structure |
---|---|---|---|
EDTA | some reversal by MgCl2, CoCl2 restores activity and stimulates above the control value | Homo sapiens | |
fructose 1,6-diphosphate | 72% inhibition at 0.2 mM and 90% inhibition at 0.7 mM | Homo sapiens | |
fructose-6-phosphate | 20% inhibition at 0.3 mM, 30% inhibition at 0.9 mM | Homo sapiens | |
glucosamine 6-phosphate | 87% inhibition at 0.4 mM, 95% inhibition at 1.2 mM | Homo sapiens | |
glucose 6-phosphate | 55% inhibition at 0.35 mM, 80% inhibition at 1.1 mM | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.029 | - |
N-acetylglucosamine 6-phosphate | - |
Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Co2+ | restores activity after treatment with EDTA and stimulates above the control value | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-acetyl-D-glucosamine 6-phosphate + H2O | Homo sapiens | pathway of N-acetylglucosamine metabolism | D-glucosamine 6-phosphate + acetate | - |
? | |
N-acetyl-D-glucosamine 6-phosphate + H2O | Plasmodium falciparum | pathway of N-acetylglucosamine metabolism | D-glucosamine 6-phosphate + acetate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Plasmodium falciparum | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Homo sapiens |
Storage Stability | Organism |
---|---|
4°C, 10 mM Tris-HCl, pH 7.5, 25% glycerol, 2 mM CHAPS, stable for at least 2 months | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-acetyl-D-glucosamine 6-phosphate + H2O | - |
Homo sapiens | D-glucosamine 6-phosphate + acetate | - |
? | |
N-acetyl-D-glucosamine 6-phosphate + H2O | - |
Plasmodium falciparum | D-glucosamine 6-phosphate + acetate | - |
? | |
N-acetyl-D-glucosamine 6-phosphate + H2O | pathway of N-acetylglucosamine metabolism | Homo sapiens | D-glucosamine 6-phosphate + acetate | - |
? | |
N-acetyl-D-glucosamine 6-phosphate + H2O | pathway of N-acetylglucosamine metabolism | Plasmodium falciparum | D-glucosamine 6-phosphate + acetate | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
- |
Homo sapiens |