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Literature summary for 3.5.1.24 extracted from
- Hypocholesteremic effect of bile salt hydrolase from Lactobacillus buchneri ATCC 4005 (2009), Food Res. Int., 42, 516-520.
No PubMed abstract available
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | effect of oral administration to Wistar rats of the immobilized bile salt hydrolase enzyme on serum cholesterol, triglyceride, high density lipoprotein levels and its application in the therapeutic treatment of hypercholesteremia, overview | Lentilactobacillus buchneri |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | BSH from ATCC 4005 is immobilized in 0.5% gellan gum gel, method, overview | Lentilactobacillus buchneri |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Lentilactobacillus buchneri | - |
strains ATCC 4005 and NCIM 2357 | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cell culture | optimization of culture conditions for the production of bile salt hydrolase, overview. Porduction is highest in sucrose- and peptone-grown cells | Lentilactobacillus buchneri | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 33.09 | - |
immobilized enzyme, pH 6.5, 37°C | Lentilactobacillus buchneri |
| 51.29 | - |
free enzyme, pH 6.5, 37°C | Lentilactobacillus buchneri |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glycodeoxycholate + H2O | - |
Lentilactobacillus buchneri | 3alpha,12alpha-dihydroxy-5-beta-cholanate + glycine | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| bile salt hydrolase | - |
Lentilactobacillus buchneri |
| BSH | - |
Lentilactobacillus buchneri |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
- |
Lentilactobacillus buchneri |
Temperature Range [°C]
| Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 20 | 60 | activity range, profile overview | Lentilactobacillus buchneri |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
- |
Lentilactobacillus buchneri |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 3 | 11 | activity range, profile overview | Lentilactobacillus buchneri |
General Information
| General Information | Comment | Organism |
|---|---|---|
| additional information | effect of oral administration to Wistar rats of the immobilized bile salt hydrolase enzyme on serum cholesterol, triglyceride, high density lipoprotein levels and its application in the therapeutic treatment of hypercholesteremia, overview | Lentilactobacillus buchneri |
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