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Literature summary for 3.5.1.24 extracted from
- Xanthomonas maltophilia CBS 897.97 as a source of new 7beta- and 7alpha-hydroxysteroid dehydrogenases and cholylglycine hydrolase: improved biotransformations of bile acids (2006), Steroids, 71, 189-198.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| cholate | uncompetitive inhibition of glycocholic acid hydrolysis | Stenotrophomonas maltophilia |  |
| taurine | uncompetitive inhibition of glycocholic acid hydrolysis | Stenotrophomonas maltophilia | |
| taurocholic acid | competitive inhibition of glycocholic acid hydrolysis | Stenotrophomonas maltophilia | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Stenotrophomonas maltophilia | - |
i.e. Stenotrophomonas maltophilia | - |
| Stenotrophomonas maltophilia CBS 897.97 | - |
i.e. Stenotrophomonas maltophilia | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| bile | - |
Bos taurus | - |
| commercial preparation | from bile | Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glycochenodeoxycholate + H2O | - |
Bos taurus | glycine + chenodeoxycholate | - |
? | |
| glycochenodeoxycholate + H2O | - |
Stenotrophomonas maltophilia | glycine + chenodeoxycholate | - |
? | |
| glycochenodeoxycholate + H2O | - |
Stenotrophomonas maltophilia CBS 897.97 | glycine + chenodeoxycholate | - |
? | |
| glycocholate + H2O | - |
Bos taurus | glycine + cholate | - |
? | |
| glycocholate + H2O | - |
Stenotrophomonas maltophilia | glycine + cholate | - |
? | |
| glycocholate + H2O | - |
Stenotrophomonas maltophilia CBS 897.97 | glycine + cholate | - |
? | |
| glycodeoxycholate + H2O | - |
Bos taurus | glycine + deoxycholate | - |
? | |
| glycodeoxycholate + H2O | - |
Stenotrophomonas maltophilia | glycine + deoxycholate | - |
? | |
| glycodeoxycholate + H2O | - |
Stenotrophomonas maltophilia CBS 897.97 | glycine + deoxycholate | - |
? | |
| glycohyodeoxycholate + H2O | - |
Stenotrophomonas maltophilia | glycine + hyodeoxycholate | - |
? | |
| glycohyodeoxycholate + H2O | - |
Stenotrophomonas maltophilia CBS 897.97 | glycine + hyodeoxycholate | - |
? | |
| glycoursodeoxycholate + H2O | - |
Stenotrophomonas maltophilia | glycine + ursodeoxycholate | - |
? | |
| glycoursodeoxycholate + H2O | - |
Stenotrophomonas maltophilia CBS 897.97 | glycine + ursodeoxycholate | - |
? | |
| taurochenodeoxycholate + H2O | - |
Bos taurus | taurine + chenodeoxycholate | - |
? | |
| taurocholate + H2O | - |
Bos taurus | taurine + cholate | - |
? | |
| taurodeoxycholate + H2O | - |
Bos taurus | taurine + deoxycholate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CGH | - |
Bos taurus |
| CGH | - |
Stenotrophomonas maltophilia |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 50 | - |
- |
Stenotrophomonas maltophilia |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 55 | - |
75 min, completely stable | Stenotrophomonas maltophilia |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
- |
Stenotrophomonas maltophilia |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 2.5 | - |
taurine | pH 8.0, 50°C | Stenotrophomonas maltophilia | |
| 2.5 | - |
taurocholic acid | pH 8.0, 50°C | Stenotrophomonas maltophilia | |
| 4.7 | - |
cholate | pH 8.0, 50°C | Stenotrophomonas maltophilia | |
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Release 2023.1 (January 2023)
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