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Literature summary for 3.5.1.23 extracted from

  • Houben, E.; Hachem, J.P.; De Paepe, K.; Rogiers, V.
    Epidermal ceramidase activity regulates epidermal desquamation via stratum corneum acidification (2008), Skin Pharmacol. Physiol., 21, 111-118.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
N-oleylethanolamine
-
Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus cleaves the N-acyl linkage of ceramides into a sphingosine base and a free fatty acid ?
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
epidermis
-
Mus musculus
-
skin
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information cleaves the N-acyl linkage of ceramides into a sphingosine base and a free fatty acid Mus musculus ?
-
?
N-palmitoyl-D-erythro-sphingosine + H2O
-
Mus musculus D-erythro-sphingosine + palmitic acid
-
?

Synonyms

Synonyms Comment Organism
CDase
-
Mus musculus
ceramidase
-
Mus musculus