Inhibitors | Comment | Organism | Structure |
---|---|---|---|
lysophosphatidic acid | isoenzyme I only | Cavia porcellus | |
additional information | no inhibition by phosphatidylethanolamine, phosphatidylinositol, phosphatidylglycerol | Cavia porcellus | |
phosphatidylcholine | - |
Cavia porcellus | |
sphingomyelin | - |
Cavia porcellus | |
sphingosine | - |
Cavia porcellus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
62000 | - |
isoenzyme II, gel filtration | Cavia porcellus |
150000 | - |
isoenzyme I, gel filtration, SDS-PAGE | Cavia porcellus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cavia porcellus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
1133.54fold, isoenzyme I, 404.32fold, isoenzyme II | Cavia porcellus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
skin | epidermal sheets | Cavia porcellus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
2.04 | - |
isoenzyme II | Cavia porcellus |
5.72 | - |
isoenzyme I | Cavia porcellus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
linoleoylsphingosine + H2O | - |
Cavia porcellus | linoleic acid + sphingosine | - |
? | |
N-oleoylsphingosine + H2O | - |
Cavia porcellus | oleic acid + sphingosine | - |
? | |
N-palmitoylsphingosine + H2O | - |
Cavia porcellus | palmitic acid + sphingosine | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | 10 | isoenzyme I | Cavia porcellus |
8 | 9 | isoenzyme II | Cavia porcellus |