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Literature summary for extracted from

  • Mahawar, M.; Kirimanjeswara, G.S.; Metzger, D.W.; Bakshi, C.S.
    Contribution of citrulline ureidase to Francisella tularensis strain Schu S4 pathogenesis (2009), J. Bacteriol., 191, 4798-4806.
    View publication on PubMedView publication on EuropePMC


Protein Variants Comment Organism
additional information generation of a nonpolar deletion DELTActu mutant. Deletion of the ctu gene results in loss of CTU activity, which is restored by transcomplementing the ctu gene. Loss of CTU does not affect acellular growth, but attenuates intramacrophage survival. Mice infected intranasally with the DELTActu mutant show significantly reduced bacterial burden in the lungs, liver, and spleen compared to wild-type Schu S4-infected mice. Francisella tularensis


Organism UniProt Comment Textmining
Francisella tularensis
strain Schu S4, gene ctu or FTT0435


Synonyms Comment Organism
citrulline ureidase
Francisella tularensis
Francisella tularensis