Cloned (Comment) | Organism |
---|---|
overexpression of GLS2 reduces the growth of tumor cells and colony formation | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
GLS2 | - |
Homo sapiens |
phosphate-activated glutaminase | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | GLS2 expression is reduced in liver tumors | down |
Homo sapiens | is induced in response to DNA damage or oxidative stress in a p53-dependent manner, and p53 associates with the GLS promotor | up |
General Information | Comment | Organism |
---|---|---|
physiological function | GLS2 probably controls the intracellular reactive oxygen species (ROS) and the apoptotic response fascilitating the ability of p53 to protect cells from accumulation of genomic damage and allows cells to survive after mild and repairable genotoxic stress | Homo sapiens |