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Literature summary for 3.5.1.2 extracted from

  • Shenoy, V.; Roig, J.C.; Kubilis, P.; Neu, J.
    Characterization of glutaminase in the developing rat small intestine (1996), J. Nutr., 126, 1121S-1130S.
    View publication on PubMed
Search for more literature for 3.5.1.2

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion mitochondrial enzyme with a cytosolic precursor Rattus norvegicus 5739
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-Gln + H2O Rattus norvegicus enzyme is involved in deamination of Gln to Glu, which is utilized for energy production via the TCA cycle. Glutaminase mRNA increases around the 3rd week of life L-Glu + NH3
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Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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Source Tissue

Source Tissue Comment Organism Textmining
small intestine preferentially localized to the surface epithelium of the small inestine, some activity is also found in cells of the lamina propria Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gln + H2O
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 Rattus norvegicus Glu + NH3
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 ?
L-Gln + H2O enzyme is involved in deamination of Gln to Glu, which is utilized for energy production via the TCA cycle. Glutaminase mRNA increases around the 3rd week of life Rattus norvegicus L-Glu + NH3
-
 ?