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Literature summary for 3.5.1.2 extracted from

  • Roberts, E.
    Glutaminase (1960), The Enzymes, 2nd Ed (Boyer, P. D. , Lardy, H. , Myrbäck, K. , eds. ), 4, 285-300.
No PubMed abstract available
Search for more literature for 3.5.1.2

Inhibitors

Inhibitors Comment Organism Structure
1,2-naphthoquinone 4-sulfonate
-
 Canis lupus familiaris
1,4-Naphthoquinone
-
 Canis lupus familiaris
1-amino-8-naphthol-2,4-disulfonic acid weak Canis lupus familiaris
2,4-dinitro-1-naphthol-7-sulfonic acid i.e. flavianic acid Canis lupus familiaris
anthraquinone-1,8-disulfonate
-
 Canis lupus familiaris
arsenate 0.5 M, 74% inhibition Sus scrofa
bicarbonate 0.5 M, complete inhibition Sus scrofa
Bromocresol green
-
 Canis lupus familiaris
bromocresol purple
-
 Canis lupus familiaris
Cl- 0.5 M, complete inhibition Sus scrofa
CN- 0.5 M, complete inhibition Sus scrofa
diphosphate 0.1 M, 98% inhibition Sus scrofa
Evans blue
-
 Canis lupus familiaris
glutamate
-
 Canis lupus familiaris
glutamate
-
 Sus scrofa
Hg2+ HgCl2 Canis lupus familiaris
iodoacetamide
-
 Canis lupus familiaris
NEM
-
 Canis lupus familiaris
NEM
-
 Sus scrofa
NH4+
-
 Canis lupus familiaris
NH4+
-
 Sus scrofa
nitrite 0.5 M, complete inhibition Sus scrofa
p-benzoquinone
-
 Canis lupus familiaris
p-mercuribenzoate
-
 Canis lupus familiaris
pyruvate 0.5 M, complete inhibition Sus scrofa
Tris 0.5 M, complete inhibition Sus scrofa

Organism

Organism UniProt Comment Textmining
Canis lupus familiaris
-
-
-
Clostridium welchii
-
-
-
Sus scrofa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Sus scrofa
-
 Canis lupus familiaris

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Sus scrofa
-
kidney
-
 Canis lupus familiaris
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-methyl-DL-Gln + H2O
-
 Canis lupus familiaris ?
-
 ?
gamma-glutamyl-methylamide + H2O no activity Canis lupus familiaris Glu + N-methylhydroxylamine
-
 ?
Gln + H2O
-
 Sus scrofa Glu + NH3
-
 ?
Gln + H2O
-
 Canis lupus familiaris Glu + NH3
-
 ?
Gln + H2O
-
 Clostridium welchii Glu + NH3
-
 r
L-Asn + H2O no activity Canis lupus familiaris L-Asp + NH3
-
 ?
L-gamma-glutamyl-hydrazide + H2O
-
 Canis lupus familiaris L-Glu + hydroxyhydrazine
-
 ?
L-gamma-glutamyl-methylester + H2O no activity Canis lupus familiaris L-Glu + methanol
-
 ?
L-isoglutamine + H2O
-
 Canis lupus familiaris ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.9 8.1
-
 Sus scrofa
7.9 8.1
-
 Canis lupus familiaris