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Literature summary for 3.5.1.19 extracted from

  • Frothingham, R.; Meeker-OæConnell, W.A.; Talbot, E.A.S.; George, J.W.; Kreuzer K.N.
    Identification, cloning, and expression of the Escherichia coli pyrazinamidase and nicotinamidase gene, pncA (1996), Antimicrob. Agents Chemother., 40, 1426-1431.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
a single enzyme accounts for both pyrazinamidase activity and nicotinamidase activity Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
nicotinamide + H2O
-
Escherichia coli nicotinate + NH3
-
?
pyrazinamide + H2O
-
Escherichia coli pyrazinoic acid + NH3
-
?

Synonyms

Synonyms Comment Organism
PZAase a single enzyme accounts for both pyrazinamidase activity and nicotinamidase activity Escherichia coli