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Literature summary for 3.5.1.19 extracted from

  • Petrack, B.; Greengard, P.; Craston, N.; Sheppy, F.
    Nicotinamide deaminase from mammalian liver (1965), J. Biol. Chem., 240, 1725-1730.
    View publication on PubMed
Search for more literature for 3.5.1.19

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
50
-
 nicotinamide
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-
microsome
-
 Oryctolagus cuniculus
-
-
mitochondrion
-
 Rattus norvegicus 5739
-

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
-
-
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus
-
 Oryctolagus cuniculus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-
liver
-
 Oryctolagus cuniculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Rattus norvegicus
additional information
-
-
 Oryctolagus cuniculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
nicotinamide + H2O
-
 Rattus norvegicus nicotinate + NH3
-
 ?
nicotinamide + H2O
-
 Oryctolagus cuniculus nicotinate + NH3
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
9 10
-
 Rattus norvegicus

pH Range

pH Minimum pH Maximum Comment Organism
7 11 pH 7.0: about 35% of maximal activity, pH 11.0: about 30% of maximal activity Rattus norvegicus