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Literature summary for 3.5.1.14 extracted from

  • Ngamsom, B.; Hickey, A.; Greenway, G.; Littlechild, J.; Watts, P.; Wiles, C.
    Development of a high throughput screening tool for biotransformations utilising a thermophilic L-aminoacylase enzyme (2010), J. Mol. Catal. B, 63, 81-86.
No PubMed abstract available
Search for more literature for 3.5.1.14

Organic Solvent Stability

Organic Solvent Comment Organism
DMSO 20% decrease in activity of immobilised enzyme at 5% (v/v) DMSO Thermococcus litoralis

Organism

Organism UniProt Comment Textmining
Thermococcus litoralis
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the order of preferred substrates is Phe > Thr > Leu > Arg for N-benzoyl substrates and Phe >> Ser > Leu > Met > Tyr > Trp for N-acetyl substrates Thermococcus litoralis additional information
-
 ?
N-acetyl-L-leucine + H2O immobilised enzyme Thermococcus litoralis acetate + L-leucine
-
 ?
N-acetyl-L-methionine + H2O immobilised enzyme Thermococcus litoralis acetate + L-methionine
-
 ?
N-acetyl-L-phenylalanine + H2O immobilised enzyme, no activity observed with N-acetyl-L-lysine Thermococcus litoralis acetate + L-phenylalanine
-
 ?
N-acetyl-L-serine + H2O immobilised enzyme Thermococcus litoralis acetate + L-serine
-
 ?
N-acetyl-L-tryptophan + H2O immobilised enzyme Thermococcus litoralis acetate + L-tryptophan
-
 ?
N-acetyl-L-tyrosine + H2O immobilised enzyme Thermococcus litoralis acetate + L-tyrosine
-
 ?
N-benzoyl-L-arginine + H2O immobilised enzyme Thermococcus litoralis benzoate + L-arginine
-
 ?
N-benzoyl-L-leucine + H2O immobilised enzyme Thermococcus litoralis benzoate + L-leucine
-
 ?
N-benzoyl-L-phenylalanine + H2O immobilised enzyme Thermococcus litoralis benzoate + L-phenylalanine
-
 ?
N-benzoyl-L-threonine + H2O immobilised enzyme Thermococcus litoralis benzoate + L-threonine
-
 ?
N-CBZ-L-phenylalanine + H2O immobilised enzyme Thermococcus litoralis ? + L-phenylalanine
-
 ?
N-chloroacetyl-L-phenylalanine + H2O immobilised enzyme Thermococcus litoralis chloroacetate + L-phenylalanine
-
 ?
N-t-BOC-L-phenylalanine + H2O immobilised enzyme Thermococcus litoralis ? + L-phenylalanine
-
 ?

Synonyms

Synonyms Comment Organism
L-aminoacylase
-
 Thermococcus litoralis