Literature summary for 3.5.1.1 extracted from

Geckil, H.; Gencer, S.; Ates, B.; Ozer, U.; Uckun, M.; Yilmaz, I.
Effect of Vitreoscilla hemoglobin on production of a chemotherapeutic enzyme, L-asparaginase, by Pseudomonas aeruginosa (2006), Biotechnol. J., 1, 203-208.

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Application

Application	Comment	Organism
pharmacology	L-asparaginase is a cancer chemotherapeutically important enzyme	Pseudomonas aeruginosa

Protein Variants

Protein Variants	Comment	Organism
additional information	recombinant expression of Vitreoscilla hemoglobin, VHb, in Pseudomonas aeruginosa strain PaJC, the L-asparaginase expression in the recombinant strain is stimulated by glucose, while it is slightly repressed in the wild-type strain NRRL B771, and shows increased enzyme production due to increased oxygen uptake caused by VHb and preference for glucose to other sugars as growth carbon source, optimization of L-asparaginase production, overview	Pseudomonas aeruginosa

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	glucose, in supplemented culture medium, causes a slight suppression of enzyme expression in wild-type strain NRRL B771	Pseudomonas aeruginosa

Organism

Organism	UniProt	Comment	Textmining
Pseudomonas aeruginosa	-	-	-
Pseudomonas aeruginosa NRRL B771	-	-	-

Synonyms

Synonyms	Comment	Organism
L-asparaginase	-	Pseudomonas aeruginosa

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Release 2023.1 (January 2023)