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Literature summary for 3.4.99.B1 extracted from

  • Gillespie, J.R.; Yokoyama, K.; Lu, K.; Eastman, R.T.; Bollinger, J.G.; Van Voorhis, W.C.; Gelb, M.H.; Buckner, F.S.
    C-terminal proteolysis of prenylated proteins in trypanosomatids and RNA interference of enzymes required for the post-translational processing pathway of farnesylated proteins (2007), Mol. Biochem. Parasitol., 153, 115-124.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
membranes from Sf9 cells expressing the RCE1 ortholog of Leishmania major show proteolytic activity against farnesylated RAS-CVIM Leishmania major
membranes from Sf9 cells expressing the RCE1 ortholog of Trypanosoma brucei show proteolytic activity against farnesylated RAS-CVIM Trypanosoma brucei

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Trypanosoma brucei the Trypanosoma brucei RCE1 ortholog appears to be the dominant prenyl-CaaX protease ?
-
?

Organism

Organism UniProt Comment Textmining
Leishmania major
-
-
-
Trypanosoma brucei
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the Trypanosoma brucei RCE1 ortholog appears to be the dominant prenyl-CaaX protease Trypanosoma brucei ?
-
?

Synonyms

Synonyms Comment Organism
Ras converting enzyme 1
-
Trypanosoma brucei
Ras converting enzyme 1
-
Leishmania major
RCE1
-
Trypanosoma brucei
RCE1
-
Leishmania major