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Literature summary for 3.4.25.2 extracted from

  • Barboza, N.R.; Cardoso, J.; de Paula Lima, C.V.; Soares, M.J.; Gradia, D.F.; Hangai, N.S.; Bahia, M.T.; Lana, M.; Krieger, M.A.; Sa, R.G.
    Expression profile and subcellular localization of HslV, the proteasome related protease from Trypanosoma cruzi (2012), Exp. Parasitol., 130, 171-177.
    View publication on PubMed
Search for more literature for 3.4.25.2

Inhibitors

Inhibitors Comment Organism Structure
additional information PSI, a classical proteasome inhibitor, does not influence the co-expression level of HslV and proteasome 20 in strain Be-78; PSI, a classical proteasome inhibitor, influences the co-expression level of HslV and proteasome 20 in strain Be-62 Trypanosoma cruzi

Localization

Localization Comment Organism GeneOntology No. Textmining
kinetoplast HslV is localized in the kinetoplast of epimastigotes Trypanosoma cruzi 20023
-

Organism

Organism UniProt Comment Textmining
Trypanosoma cruzi
-
-
-
Trypanosoma cruzi
-
 strain Berenice 62
-
Trypanosoma cruzi
-
 strain Berenice 78
-
Trypanosoma cruzi Be-62
-
 strain Berenice 62
-
Trypanosoma cruzi Be-78
-
 strain Berenice 78
-
Trypanosoma cruzi Dcm28
-
-
-
Trypanosoma cruzi Y
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
epimastigote HslV is localized in the kinetoplast of epimastigotes Trypanosoma cruzi
-
additional information HslV and 20S proteasome are differently expressed in strain Be-62 Trypanosoma cruzi
-
additional information HslV and 20S proteasome are differently expressed in strain Be-78 Trypanosoma cruzi
-
additional information HslV and 20S proteasome are differently expressed in strain Y Trypanosoma cruzi
-

Synonyms

Synonyms Comment Organism
HslU/HslV
-
 Trypanosoma cruzi
HslV
-
 Trypanosoma cruzi
HslV peptidase
-
 Trypanosoma cruzi
hslVU
-
 Trypanosoma cruzi

Cofactor

Cofactor Comment Organism Structure
ATP dependent on Trypanosoma cruzi

General Information

General Information Comment Organism
additional information the enzyme is part of the HslVU enzyme complex, HslVU is an ATP-dependent protease consisting of two multimeric components: the HslU ATPase and the HslV peptidase, interaction between HslU and HslV Trypanosoma cruzi
additional information the enzyme is part of the HslVU enzyme complex, HslVU is an ATP-dependent protease consisting of two multimeric components: the HslU ATPase and the HslV peptidase, interaction between HslU and HslV. PSI, a classical proteasome inhibitor, does not influence the co-expression level of HslV and proteasome 20 in strain Be-78 Trypanosoma cruzi
additional information the enzyme is part of the HslVU enzyme complex, HslVU is an ATP-dependent protease consisting of two multimeric components: the HslU ATPase and the HslV peptidase, interaction between HslU and HslV. PSI, a classical proteasome inhibitor, influences the co-expression level of HslV and proteasome 20 in strain Be-62 Trypanosoma cruzi
additional information the enzyme is part of the HslVU enzyme complex, HslVU is an ATP-dependent protease consisting of two multimeric components: the HslU ATPase and the HslV peptidase, interaction between HslU and HslV. PSI, a classical proteasome inhibitor, influences the co-expression level of HslV and proteasome 20 in strain Y Trypanosoma cruzi
physiological function the enzyme is involved in a non-lysosomal degradation pathway important for Trypanosoma cruzi biology Trypanosoma cruzi