Literature summary for 3.4.25.2 extracted from

Azim, M.K.; Noor, S.
Characterization of protomer interfaces in HslV protease, the bacterial homologue of 20S proteasome (2007), Protein J., 26, 213-219.

Search for more literature for 3.4.25.2

Activating Compound

Activating Compound	Comment	Organism	Structure
HslU	HslV protomer interfaces perform distinct functions: whereas intra-ring interface participates in HslV:HslU interaction resulting in allosteric activation of HslV protease by HslU, the interring interfaces uphold the oligomeric form of HslV	Haemophilus influenzae
HslU	HslV protomer interfaces perform distinct functions: whereas intra-ring interface participates in HslV:HslU interaction resulting in allosteric activation of HslV protease by HslU, the interring interfaces uphold the oligomeric form of HslV	Escherichia coli
HslU	HslV protomer interfaces perform distinct functions: whereas intra-ring interface participates in HslV:HslU interaction resulting in allosteric activation of HslV protease by HslU, the interring interfaces uphold the oligomeric form of HslV	Thermotoga maritima

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-
Haemophilus influenzae	-	-	-
Thermotoga maritima	-	-	-

Subunits

Subunits	Comment	Organism
dodecamer	HslVU, a two-component proteasome-related prokaryotic system is composed of HslV protease and HslU ATPase. HslV protomers assemble in a dodecamer of two-stacked hexameric rings that form a complex with HslU hexamers. Structural analyses of protomer interfaces in HslV dodecamer suggests that HslV interfaces involve extensive area in which major determinants for function and stability constitute hot spots	Escherichia coli
dodecamer	HslVU, a two-component proteasome-related prokaryotic system is composed of HslV protease and HslU ATPase. HslV protomers assemble in a dodecamer of two-stacked hexameric rings that form a complex with HslU hexamers. Structural analysis of protomer interfaces in HslV dodecamer suggests that HslV interfaces involve extensive area in which major determinants for function and stability constitute hot spots	Thermotoga maritima

Synonyms

Synonyms	Comment	Organism
HslV protease	-	Haemophilus influenzae
HslV protease	-	Escherichia coli
HslV protease	-	Thermotoga maritima

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)