Literature summary for 3.4.25.1 extracted from

Harshbarger, W.; Miller, C.; Diedrich, C.; Sacchettini, J.
Crystal structure of the human 20S proteasome in complex with carfilzomib (2015), Structure, 23, 418-424.

Search for more literature for 3.4.25.1

Crystallization (Commentary)

Crystallization (Comment)	Organism
in complex with carfilzomib, hanging drop vapor diffusion method, using 0.2 M sodium formate, 40% (w/v) 2-methyl-2,4-pentanediol, at 16°C	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
carfilzomib	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P25789	(subunit alpha 4), P49720 (subunit beta 3), P28072 (subunit beta 6), P25786 (subunit alpha 1), P25787 (subunit alpha 2), P28066 (subunit alpha 5), P60900 (subunit alpha 6), O14818 (subunit alpha 7), P20618 (subunit beta 1), P49721 (subunit beta 2), P28070 (subunit beta 4), P28074 (subunit beta 5), Q99436 (subunit beta 7), P25788 (subunit alpha 3)	-

Purification (Commentary)

Purification (Comment)	Organism
HiTrap phenyl-Sepharose column chromatography	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
erythrocyte	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
20S proteasome	-	Homo sapiens

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Release 2023.1 (January 2023)