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Literature summary for 3.4.25.1 extracted from

  • Alvarez-Castelao, B.; Martin-Guerrero, I.; Garcia-Orad, A.; Castano, J.G.
    Cytomegalovirus promoter up-regulation is the major cause of increased protein levels of unstable reporter proteins after treatment of living cells with proteasome inhibitors (2009), J. Biol. Chem., 284, 28253-28262.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
epoxomycin effect on mRNA and protein abundance in HeLa cells, overview Homo sapiens
epoxomycin effect on mRNA and protein abundance in NIH-3T3 and N2A cells, overview Mus musculus
epoxomycin effect on mRNA and protein abundance in PC-12 cells, overview Rattus norvegicus
lactacystin effect on mRNA and protein abundance in HeLa cells, overview Homo sapiens
lactacystin effect on mRNA and protein abundance in NIH-3T3 and N2A cells, overview Mus musculus
lactacystin effect on mRNA and protein abundance in PC-12 cells, overview Rattus norvegicus
MG132 effect on mRNA and protein abundance in HeLa cells, overview Homo sapiens
MG132 effect on mRNA and protein abundance in NIH-3T3 and N2A cells, overview Mus musculus
MG132 effect on mRNA and protein abundance in PC-12 cells Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell
-
Homo sapiens
-
Neuro-2a cell neuroblastoma cell line Mus musculus
-
NIH-3T3 cell
-
Mus musculus
-
PC-12 cell pheochromocytoma cells Rattus norvegicus
-

Synonyms

Synonyms Comment Organism
26 S proteasome
-
Mus musculus
26 S proteasome
-
Homo sapiens
26 S proteasome
-
Rattus norvegicus
proteasome
-
Mus musculus
proteasome
-
Homo sapiens
proteasome
-
Rattus norvegicus

General Information

General Information Comment Organism
metabolism the expression of unstable proteins is regulated by transcriptional regulation and not by degradation of the unstable protein by the ubiquitin/proteasome system, overview Mus musculus
metabolism the expression of unstable proteins is regulated by transcriptional regulation and not by degradation of the unstable protein by the ubiquitin/proteasome system, overview Homo sapiens
metabolism the expression of unstable proteins is regulated by transcriptional regulation and not by degradation of the unstable protein by the ubiquitin/proteasome system, overview Rattus norvegicus