Activating Compound | Comment | Organism | Structure |
---|---|---|---|
3H-1,2-dithiole-3-thione | tissue specific increase of the catalytic subunits of the proteasome following oral administration of 0.5 mmol/kg | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
MG132 | 0.02 mM | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cerebral cortex | - |
Mus musculus | - |
colon | - |
Mus musculus | - |
hippocampus | - |
Mus musculus | - |
liver | - |
Mus musculus | - |
lung | - |
Mus musculus | - |
N1E-115 cell | - |
Mus musculus | - |
small intestine | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
succinyl-Leu-Leu-Val-Tyr-7-amido-4-methylcoumarin + H2O | - |
Mus musculus | ? | - |
? | |
Z-Ala-Arg-Arg-7-amido-4-methylcoumarin + H2O | - |
Mus musculus | ? | - |
? | |
Z-Leu-Leu-Glu-7-amido-4-methylcoumarin + H2O | - |
Mus musculus | Z-Leu-Leu-Glu + 7-amino-4-methylcoumarin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
20S proteasome | - |
Mus musculus |
26S proteasome | - |
Mus musculus |