Any feedback?
Literature summary for 3.4.25.1 extracted from
- Isolation and characterization of bovine thymus multicatalytic proteinase complex (2000), Protein Expr. Purif., 18, 160-168.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 3,4-dichloroisocoumarin | benzyloxycarbonyl-GGL-4-nitroanilide as substrate | Bos taurus |  |
| benzyloxycarbonyl-GPAF aldehyde | - |
Bos taurus | |
| benzyloxycarbonyl-GPFL aldehyde | - |
Bos taurus | |
| benzyloxycarbonyl-LLF aldehyde | - |
Bos taurus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.14 | - |
benzyloxycarbonyl-GPALG-4-aminobenzoate | enzyme from spleen | Bos taurus | |
| 0.38 | - |
benzyloxycarbonyl-GPAFG-4-aminobenzoate | enzyme from spleen | Bos taurus | |
| 0.57 | - |
benzyloxycarbonyl-GPALG-4-aminobenzoate | enzyme from thymus | Bos taurus | |
| 0.8 | - |
benzyloxycarbonyl-GPAFG-4-aminobenzoate | enzyme from thymus | Bos taurus | |
| 2.29 | - |
benzyloxycarbonyl-GGF-4-aminobenzoate | enzyme from thymus | Bos taurus | |
| 3.3 | - |
benzyloxycarbonyl-GPAFG-4-aminobenzoate | enzyme from pituitary | Bos taurus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| thymus | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| benzyloxycarbonyl-D-Ala-Leu-Arg-4-nitroanilide + H2O | - |
Bos taurus | ? | - |
? | |
| benzyloxycarbonyl-GAPLG-p-aminobenzoate + H2O | - |
Bos taurus | ? | - |
? | |
| benzyloxycarbonyl-GGF-4-aminobenzoate + H2O | - |
Bos taurus | ? | - |
? | |
| benzyloxycarbonyl-GGF-p-aminobenzoate + H2O | - |
Bos taurus | ? | - |
? | |
| benzyloxycarbonyl-GGL-2-naphthylamide + H2O | - |
Bos taurus | ? | - |
? | |
| benzyloxycarbonyl-GPAFG-4-aminobenzoate + H2O | - |
Bos taurus | ? | - |
? | |
| benzyloxycarbonyl-GPAFG-p-aminobenzoate + H2O | - |
Bos taurus | ? | - |
? | |
| benzyloxycarbonyl-GPAGG-4-nitroanilide + H2O | - |
Bos taurus | ? | - |
? | |
| benzyloxycarbonyl-GPALG-4-aminobenzoate + H2O | - |
Bos taurus | ? | - |
? | |
| benzyloxycarbonyl-GPALG-p-aminobenzoate + H2O | - |
Bos taurus | ? | - |
? | |
| benzyloxycarbonyl-LLE-2-naphthylamide + H2O | - |
Bos taurus | ? | - |
? | |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.03 | 0.55 | benzyloxycarbonyl-GPALG-4-aminobenzoate | enzyme from thymus | Bos taurus | |
| 0.2 | - |
benzyloxycarbonyl-GGF-4-aminobenzoate | enzyme from thymus | Bos taurus | |
| 0.5 | - |
benzyloxycarbonyl-GPALG-4-aminobenzoate | enzyme from spleen | Bos taurus | |
| 1.98 | - |
benzyloxycarbonyl-GPAFG-4-aminobenzoate | enzyme from pituitary | Bos taurus | |
| 2.94 | - |
benzyloxycarbonyl-GPAFG-4-aminobenzoate | enzyme from pituitary | Bos taurus | |
| 3 | - |
benzyloxycarbonyl-GPAFG-4-aminobenzoate | enzyme from thymus | Bos taurus | |
| 3.75 | - |
benzyloxycarbonyl-GPALG-4-aminobenzoate | enzyme from pituitary | Bos taurus | |
| 7.04 | - |
benzyloxycarbonyl-GPALG-4-aminobenzoate | enzyme from thymus | Bos taurus | |
| 12.9 | - |
benzyloxycarbonyl-GPALG-4-aminobenzoate | enzyme from spleen | Bos taurus | |
| 18.8 | - |
benzyloxycarbonyl-GPAFG-4-aminobenzoate | enzyme from spleen | Bos taurus | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.00005 | - |
benzyloxycarbonyl-GPFL aldehyde | enzyme from thymus, substrate: benzyloxycarbonyl-GPAFG-p-aminobenzoate | Bos taurus | |
| 0.00082 | - |
benzyloxycarbonyl-GPFL aldehyde | enzyme from thymus, substrate: benzyloxycarbonyl-GPALG-p-aminobenzoate | Bos taurus | |
| 0.00104 | - |
benzyloxycarbonyl-GPFL aldehyde | enzyme from spleen, substrate: benzyloxycarbonyl-GPALG-p-aminobenzoate | Bos taurus | |
| 0.0016 | - |
benzyloxycarbonyl-LLF aldehyde | enzyme from pituitary, substrate: benzyloxycarbonyl-GGF-p-aminobenzoate | Bos taurus | |
| 0.002 | - |
benzyloxycarbonyl-GPAF aldehyde | enzyme from thymus, substrate: benzyloxycarbonyl-GPALG-aminobenzoate | Bos taurus | |
| 0.00251 | - |
benzyloxycarbonyl-LLF aldehyde | enzyme from thymus, substrate: benzyloxycarbonyl-GGF-p-aminobenzoate | Bos taurus | |
| 0.0026 | - |
benzyloxycarbonyl-GPAF aldehyde | enzyme from spleen, substrate: benzyloxycarbonyl-GPALG-aminobenzoate | Bos taurus | |
| 0.00466 | - |
benzyloxycarbonyl-GPFL aldehyde | enzyme from pituitary, substrate: benzyloxycarbonyl-GPALG-p-aminobenzoate | Bos taurus | |
| 0.00546 | - |
benzyloxycarbonyl-GPFL aldehyde | enzyme from thymus, substrate: benzyloxycarbonyl-GGF-p-aminobenzoate | Bos taurus | |
| 0.00597 | - |
benzyloxycarbonyl-LLF aldehyde | enzyme from spleen, substrate: benzyloxycarbonyl-GGF-p-aminobenzoate | Bos taurus | |
| 0.0162 | - |
benzyloxycarbonyl-GPFL aldehyde | enzyme from spleen, substrate: benzyloxycarbonyl-GGF-p-aminobenzoate | Bos taurus | |
| 0.0527 | - |
benzyloxycarbonyl-GPFL aldehyde | enzyme from pituitary, substrate: benzyloxycarbonyl-GGF-p-aminobenzoate | Bos taurus | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
