Any feedback?
Literature summary for 3.4.24.B8 extracted from
- A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusion (1992), Nature, 356, 248-252.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| DNA and amino acid sequence determination, alpha and beta subunits | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| plasma membrane | type I integral membrane glycoprotein, on the surface of sperm | Homo sapiens | 5886 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 44000 | - |
1 * 60000, alpha subunit, + 1 * 44000, beta subunit, SDS-PAGE | Homo sapiens |
| 60000 | - |
1 * 60000, alpha subunit, + 1 * 44000, beta subunit, SDS-PAGE | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | the enzyme mediates the cell-cell membrane fusion of egg and sperm | ? | - |
? |  |
| proteins + H2O | Homo sapiens | - |
peptides | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | N-glycosylation | Homo sapiens |
| proteolytic modification | processing of precursor to mature protein | Homo sapiens |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| sperm | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the enzyme mediates the cell-cell membrane fusion of egg and sperm | Homo sapiens | ? | - |
? | |
| proteins + H2O | - |
Homo sapiens | peptides | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 1 * 60000, alpha subunit, + 1 * 44000, beta subunit, SDS-PAGE | Homo sapiens |
| More | the alpha subunit contains a putative fusion peptide, beta subunit contains a soluble disintegrin ligand | Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| M12.201 | Merops-ID | Homo sapiens |
| PH-30 | - |
Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
