Literature summary for 3.4.24.B7 extracted from

Ahokas, K.; Skoog, T.; Suomela, S.; Jeskanen, L.; Impola, U.; Isaka, K.; Saarialho-Kere, U.
Matrilysin-2 (matrix metalloproteinase-26) is upregulated in keratinocytes during wound repair and early skin carcinogenesis (2005), J. Invest. Dermatol., 124, 849-856.

Search for more literature for 3.4.24.B7

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
hair follicle	in intact skin MMP-26 is expressed only in hair follicles	Homo sapiens	-
keratinocyte	matrilysin-2 (matrix metalloproteinase-26) is upregulated in keratinocytes during wound repair and early skin carcinogenesis. MMP-26 is expressed by laminin-5-positive keratinocytes in the migrating area during wound repair, in benign skin disorders characterized by inflammation and microdisruptions of basement membrane. MMP-26 may be upregulated in basal keratinocytes even without tumorigenesis because of altered cell-matrix interactions and inflammation	Homo sapiens	-
squamous cell carcinoma cell	MMP-26 is expressed in grade I and II squamous cell cancer. It is not present in dedifferentiated grade III tumors. MMP-26 becomes downregulated during histological dedifferentiation of squamous cell cancer cells	Homo sapiens	-

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)