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Literature summary for 3.4.24.B6 extracted from
- TGF-beta1 and TGFBR1 are expressed in ameloblasts and promote MMP20 expression (2009), Anat. Rec. (Hoboken), 292, 885-890.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
Kunming strain mice | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| ameloblast | - |
Mus musculus | - |
| mandible | from mouse embryos at E18.5 and postnatal day 3 mice | Mus musculus | - |
| additional information | MMP20 expression analysis, overview | Mus musculus | - |
| tooth | developing | Mus musculus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| enamelysin | - |
Mus musculus |
| matrix metalloproteinase 20 | - |
Mus musculus |
| MMP20 | - |
Mus musculus |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Mus musculus | transforming growth factor-beta1, TGF-beta1, prominently induces MMP20 expression in ameloblast-lineage cells | up |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | TGF-beta signaling involved in amelogenesis is partially mediated by regulating the expression of MMP20 mRNA | Mus musculus |
| physiological function | MMP20 is an early enzyme, being expressed throughout the secretory stage and into earlier maturation stage of amelogenesis, an intense remodeling and degradation of the enamel matrix by proteases facilitates the enamel biomineralization, overview | Mus musculus |
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Release 2023.1 (January 2023)
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