Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CL 82198 | specific inhibitor | Homo sapiens | |
CL 82198 | specific inhibitor | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A-375 cell | - |
Homo sapiens | - |
melan-a Hm cell | - |
Mus musculus | - |
melanocyte | - |
Mus musculus | - |
melanocyte | - |
Homo sapiens | - |
melanoma cell | - |
Mus musculus | - |
melanoma cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Gelatin + H2O | - |
Mus musculus | ? | - |
? | |
Gelatin + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MMP13 | - |
Mus musculus |
MMP13 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Mus musculus | after epidermal growth factor stimulation MMP13 is up-regulated | up |
Homo sapiens | after epidermal growth factor stimulation MMP13 is up-regulated | up |
General Information | Comment | Organism |
---|---|---|
malfunction | knockdown of MMP13 strongly enhances pigmentation of melanocytes | Mus musculus |
malfunction | knockdown of MMP13 strongly enhances pigmentation of melanocytes | Homo sapiens |
physiological function | MMP13 mediates cell proliferation in melanocytes and melanoma cells. Growth stimuli are mediated via MMP13 in melanocytes and melanoma | Mus musculus |
physiological function | MMP13 mediates cell proliferation in melanocytes and melanoma cells. Growth stimuli are mediated via MMP13 in melanocytes and melanoma | Homo sapiens |