Literature summary for 3.4.24.B4 extracted from

Ahmad, R.; El Mabrouk, M.; Sylvester, J.; Zafarullah, M.
Human osteoarthritic chondrocytes are impaired in matrix metalloproteinase-13 inhibition by IFN-gamma due to reduced IFN-gamma receptor levels (2009), Osteoarthritis Cartilage, 17, 1049-1055.

Search for more literature for 3.4.24.B4

Cloned(Commentary)

Cloned (Comment)	Organism
MMP-13 RT-PCR expression analysis, overview	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
type-II collagen + H2O	Homo sapiens	the osteoarthritic cartilage type-II collagen is preferentially cleaved by the proinflammatory cytokine-induced MMP-13	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
chondrocyte	healthy and osteoarthritic, MMP-13 RT-PCR expression analysis, overview	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
type-II collagen + H2O	the osteoarthritic cartilage type-II collagen is preferentially cleaved by the proinflammatory cytokine-induced MMP-13	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
MMP-13	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	interleukin-1beta induces MMP-13 expression, which is potently inhibited by interferon-gamma healthy chondrocytes mediated by STAT1	up

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Release 2023.1 (January 2023)