Cloned (Comment) | Organism |
---|---|
DNA and amino acid sequence determination and analysis, quantitative RT-PCR analysis expression analysis, overview. Phylogenetic analysis | Ictalurus punctatus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Ictalurus punctatus | MMP-13 preferentially hydrolyzes collagen type II, and has wide substrate specificity, allowing it to degrade several other forms of collagen and other extracellular matrix components | ? | - |
? | |
type II collagen + H2O | Ictalurus punctatus | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Ictalurus punctatus | E3SW76 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood | - |
Ictalurus punctatus | - |
brain | - |
Ictalurus punctatus | - |
embryo | - |
Ictalurus punctatus | - |
gill | - |
Ictalurus punctatus | - |
head kidney | - |
Ictalurus punctatus | - |
heart | - |
Ictalurus punctatus | - |
intestine | - |
Ictalurus punctatus | - |
liver | - |
Ictalurus punctatus | - |
additional information | MMP-13 pattern of expression in various healthy tissues and during embryogenesis, MMP-13 expression is slightly increased in the first day post-fertilization and sharply up-regulated from 1-day postfertilization through hatching, quantitative RT-PCR analysis, overview | Ictalurus punctatus | - |
muscle | - |
Ictalurus punctatus | - |
ovary | - |
Ictalurus punctatus | - |
skin | - |
Ictalurus punctatus | - |
spleen | - |
Ictalurus punctatus | - |
stomach | - |
Ictalurus punctatus | - |
trunk kidney | - |
Ictalurus punctatus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | MMP-13 preferentially hydrolyzes collagen type II, and has wide substrate specificity, allowing it to degrade several other forms of collagen and other extracellular matrix components | Ictalurus punctatus | ? | - |
? | |
type II collagen + H2O | - |
Ictalurus punctatus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
collagenase-3 | - |
Ictalurus punctatus |
MMP-13 | - |
Ictalurus punctatus |
More | MMP-13 is the third member in the collagenase subfamily of proteases | Ictalurus punctatus |
General Information | Comment | Organism |
---|---|---|
physiological function | MMP-13 is a proteolytic enzyme that plays a key role in degradation and remodelling of host extracellular matrix proteins | Ictalurus punctatus |