Cloned (Comment) | Organism |
---|---|
MMP-13 expression and promoter activity analysis, overview | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
periodontal ligament | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
MMP-13 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
additional information | Obedience in the expression of MMP-13 as extracellular matrix remodelling executioner from the activation state of mechano-transducing molecules. The transcription factor c-fos is a constituent of the AP1-complex addressing the MMP-13 promotor. Role of activated MAP-kinases pp38 and pp42/44 in strain-induced expression of the active form of MMP-13, activated, phosphorylated p42/44 and p38 are responsible for the expression of MMP-13, overview | Homo sapiens |
physiological function | MMP-13 is involved in the mechano-transduction in periodontal ligament cells, that is crucial for physiological and orthodontic tooth movement-associated periodontal remodelling | Homo sapiens |