Protein Variants | Comment | Organism |
---|---|---|
E614Q | site-directed mutagenesis, exchange of active site residue, stongly reduced activity | Saccharomyces cerevisiae |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrial inner membrane | inner side, exposes catalytic sites to the mitochondrial matrix | Saccharomyces cerevisiae | 5743 | - |
mitochondrion | - |
Saccharomyces cerevisiae | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
protein + H2O | Saccharomyces cerevisiae | - |
peptides | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
in complex with Yme1p, EC 3.4.24.B19, forming i-AAA protease | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
proteolytic degradation of proteins | conserved metal-binding site HEXXH, selective degradation, mechanism | Saccharomyces cerevisiae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
hybrid protein + H2O | hybrid protein of subunit 2 of cytochrome oxidase residues 1-74, mouse dihydrofolate reductase, and mitochondrial presequence, residues 1-66, of subunit 9 of the ATPase of Neurospora crassa, in vitro import into the mitochondrion | Saccharomyces cerevisiae | 2 peptide fragments f2 and f3 | product characterization | ? | |
additional information | Yta12p enzyme requires YTA10-12 complex formation for activity | Saccharomyces cerevisiae | ? | - |
? | |
protein + H2O | - |
Saccharomyces cerevisiae | peptides | - |
? | |
residues 1-74 of subunit 2 of cytochrome oxidase + H2O | two-step procedure, in vitro import into the mitochondrion | Saccharomyces cerevisiae | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
M41.003 | Merops-ID | Saccharomyces cerevisiae |
YTA12p | - |
Saccharomyces cerevisiae |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
assay at | Saccharomyces cerevisiae |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | dependent on | Saccharomyces cerevisiae |