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Literature summary for 3.4.24.B15 extracted from

  • Rowe, P.S.
    Regulation of bone-renal mineral and energy metabolism: the PHEX, FGF23, DMP1, MEPE ASARM pathway (2012), Crit. Rev. Eukaryot. Gene Expr., 22, 61-86.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.B15

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ a zinc metalloendopeptidase Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
bone sialoprotein + H2O Homo sapiens
-
 ?
-
 ?
dentin matrix protein-1 + H2O Homo sapiens
-
 ?
-
 ?
dentin sialophosphoprotein + H2O Homo sapiens
-
 dentin sialoprotein + dentin phosphoprotein + dentin glycoprotein
-
 ?
enamelin + H2O Homo sapiens
-
 ?
-
 ?
matrix extracellular phosphoglycoprotein + H2O Homo sapiens
-
 ?
-
 ?
osteopontin + H2O Homo sapiens
-
 ?
-
 ?
statherin + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P78562
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
bone sialoprotein + H2O
-
 Homo sapiens ?
-
 ?
dentin matrix protein-1 + H2O
-
 Homo sapiens ?
-
 ?
dentin sialophosphoprotein + H2O
-
 Homo sapiens dentin sialoprotein + dentin phosphoprotein + dentin glycoprotein
-
 ?
enamelin + H2O
-
 Homo sapiens ?
-
 ?
matrix extracellular phosphoglycoprotein + H2O
-
 Homo sapiens ?
-
 ?
osteopontin + H2O
-
 Homo sapiens ?
-
 ?
statherin + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
PEX previously known as PEX Homo sapiens
PHEX
-
 Homo sapiens
phosphate-regulating gene with homologies to endo-peptidases on the X chromosome
-
 Homo sapiens

General Information

General Information Comment Organism
malfunction enzyme defects are responsible for X-linked hypophosphatemic rickets Homo sapiens