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Literature summary for 3.4.24.B15 extracted from

  • Martin, A.; Liu, S.; David, V.; Li, H.; Karydis, A.; Feng, J.Q.; Quarles, L.D.
    Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) signaling (2011), FASEB J., 25, 2551-2562.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.B15

Organism

Organism UniProt Comment Textmining
Mus musculus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
bone
-
 Mus musculus
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femur
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 Mus musculus
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osteocyte
-
 Mus musculus
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Synonyms

Synonyms Comment Organism
PHEX
-
 Mus musculus

General Information

General Information Comment Organism
malfunction inactivation of PHEX results in equivalent intrinsic bone mineralization defects and increased fibroblastic growth factor 23 expression in osteocytes Mus musculus
physiological function PHEX and DMP1 control a common pathway regulating bone mineralization and fibroblastic growth factor 23 production, the latter involving activation of the fibroblastic growth factor receptor signaling in osteocytes Mus musculus