Literature summary for 3.4.24.B15 extracted from

Ito, M.; Akai, E.; Izuka, M.; Segawa, H.; Kuwahata, M.; Miyamoto, K.
Cloning and characterization of three PHEX homologues in Drosophila (2004), J. Bone Miner. Metab., 22, 3-11.

Search for more literature for 3.4.24.B15

Cloned(Commentary)

Cloned (Comment)	Organism
dPHEX1-3, localization on the X-chromosome, genomic organization, DNA and amino acid sequence determination and analysis, expression profiles of the isozymes in embryonic developmental stages, expression of FLAG-tagged isozymes in S2 cells	Drosophila melanogaster

Protein Variants

Protein Variants	Comment	Organism
additional information	dPHEX1 inactivation by P-element insertion, homozygous mutant fly embryos show complete lethality in the early stages	Drosophila melanogaster

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
endoplasmic reticulum	isozymes dPHEX1 and dPHEX2	Drosophila melanogaster	5783	-
Golgi apparatus	isozymes dPHEX1 and dPHEX2	Drosophila melanogaster	5794	-
plasma membrane	isozymes dPHEX3 and dPHEX2	Drosophila melanogaster	5886	-

Organism

Organism	UniProt	Comment	Textmining
Drosophila melanogaster	-	three isozymes dPHEX1-3	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
embryo	expression profiles of isozymes dPHEX1-3, dPHEX1 and dPHEX3 expression levels increase in late embryonic developmental stages, while dPHEX2 remains unaltered during the whole development	Drosophila melanogaster	-
S2 cell	isozymes dPHEX1-3	Drosophila melanogaster	-

Synonyms

Synonyms	Comment	Organism
dPHEX	-	Drosophila melanogaster
PHEX homologue	-	Drosophila melanogaster

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Release 2023.1 (January 2023)