Cloned (Comment) | Organism |
---|---|
the gene is localized on the X chromosome | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | mutation of Phex leads to the dominant disorder hypophosphatemia which is associated with a renal waste of phosphate and defective bone mineralization | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | the major regulator of bone development and turnover PTH, commercial preperation from rat, decreases osteoblastic Phex expression and matrix mineralization in vitro and in vivo, overview | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Mus musculus | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
C57BL/6J mice | - |
Mus musculus C57/BL6J | - |
C57BL/6J mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
calvarium | - |
Mus musculus | - |
MC3T3-E1 cell | osteoblastic cell line | Mus musculus | - |
osteoblast | fully differentiated, from calvaria of newborn mice | Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
PHEX | - |
Mus musculus |
phosphate-regulating gene with homologies to endopeptidases on the X chromosome | - |
Mus musculus |