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Literature summary for 3.4.24.B12 extracted from

  • Fushimi, K.; Troeberg, L.; Nakamura, H.; Lim, N.H.; Nagase, H.
    Functional differences of the catalytic and non-catalytic domains in human ADAMTS-4 and ADAMTS-5 in aggrecanolytic activity (2008), J. Biol. Chem., 283, 6706-6716.
    View publication on PubMed
Search for more literature for 3.4.24.B12

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HEK-293-EBNA cells Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
tissue inhibitor of metalloproteinases-3
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
74000
-
 predicted from amino acid sequence Homo sapiens
81000
-
 recombinant enzyme, SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
anti-FLAG M2-agarose column chromatography, Macro-Prep 25 S resin chromatography, and Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
aggrecan + H2O
-
 Homo sapiens ?
-
 ?
carboxymethylated transferrin + H2O
-
 Homo sapiens ?
-
 ?
fibromodulin + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
a disintegrin and metalloproteinase with thrombospondin type 1 motifs-5
-
 Homo sapiens
ADAMTS-5
-
 Homo sapiens
aggrecanase-2
-
 Homo sapiens