Activating Compound | Comment | Organism | Structure |
---|---|---|---|
MMP-15 | activates ADAMTS-1 | Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
110000 | - |
x * 110000, pro-form, SDS-PAGE | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
versican + H2O | Mus musculus | ADAMTS-1 cleaves versican at the Glu441-Ala442 bond to generate a 70000 Da fragment termed DPEAAE | DPEAAE + ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
endothelial cell | ADAMTS-1 is localized to developing mother vessel endothelial cells | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
versican + H2O | ADAMTS-1 cleaves versican at the Glu441-Ala442 bond to generate a 70000 Da fragment termed DPEAAE | Mus musculus | DPEAAE + ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 110000, pro-form, SDS-PAGE | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
ADAMTS-1 | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | ADAMTS-1 mRNA expression is strongly, indirectly and progressively upregulated over the period of 30 min to 16 h by vascular endothelial growth factor A | up |