Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.24.B11 extracted from

  • Hu, L.; Jonsson, K.B.; Andersen, H.; Edenro, A.; Bohlooly-Y, M.; Melhus, H.; Lind, T.
    Over-expression of Adamts1 in mice alters bone mineral density (2011), J. Bone Miner. Metab., 30, 304-311.
    View publication on PubMed

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
90000
-
x * 90000, mature secreted form of Adamts1 protein, SDS-PAGE Mus musculus
115000
-
x * 115000, full-length Adamts1 protein, SDS-PAGE Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Collagen type I + H2O Mus musculus
-
?
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
bone
-
Mus musculus
-
femur
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Collagen type I + H2O
-
Mus musculus ?
-
?

Subunits

Subunits Comment Organism
? x * 115000, full-length Adamts1 protein, SDS-PAGE Mus musculus
? x * 90000, mature secreted form of Adamts1 protein, SDS-PAGE Mus musculus

Synonyms

Synonyms Comment Organism
ADAMTS1
-
Mus musculus

General Information

General Information Comment Organism
physiological function ADAMTS1 has an impact on bone mineral density and is a potent regulator of bone remodeling. Adamts1 induces parathyroid hormone levels in females and reduces osteocalcin levels in males Mus musculus