Application | Comment | Organism |
---|---|---|
medicine | in men not on pravastatin, those homozygous for the 227Pro allele of ADAMTS1 have a nearly 2-fold increased risk of coronary heart disease events compared with noncarriers. In this high-risk group, treatment with pravastatin is highly efficacious, reducing the odds of fatal coronary disease or nonfatal myocardial infarction by approximately 75%, as compared with 25% in noncarriers or heterozygotes | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9UHI8 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
ADAMTS1 matrix metalloproteinase | - |
Homo sapiens |